When a process in interrupted then it usually keeps its environment in the cache. Reopening the process uses the cached environment setting. In some cases (mainly when you are testing new processes) it can be useful to reload values stored in the environment (like skeletons, libraries,...) from the config file.
To activate it, set this option to true. Then the environment is always reloaded when interrupted process is started. Please note that not all environment settings can be reloaded, for example, task names can't change.